Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 7/20 | 0.42 |
| ▸ | ACE | P12821 | 5/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 4/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037329 | 1.00 | KIFC1 (0.43) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL17968745 | 0.93 | KIFC1 (0.43) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL15037392 | 0.93 | KIFC1 (0.43) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL15037324 | 0.93 | MME (0.42) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL15019730 | 0.93 | CA1 (0.44) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL15019733 | 0.93 | CA1 (0.44) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL17834867 | 0.93 | KIFC1 (0.43) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL15037133 | 0.93 | KIFC1 (0.43) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL22449054 | 0.92 | KIFC1 (0.48) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL15037327 | 0.92 | KIFC1 (0.48) | KIFC1MMEACEACE2ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |