Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.60 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037285 | 1.00 | ITGB1 (0.60) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL22449214 | 0.96 | ITGB3 (0.59) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL15037175 | 0.96 | ITGB3 (0.59) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL15100180 | 0.94 | ITGB3 (0.63) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL22449199 | 0.94 | ITGB3 (0.56) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL15100148 | 0.94 | ITGB3 (0.56) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL15037274 | 0.94 | ITGB3 (0.56) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL22448946 | 0.93 | ITGB3 (0.56) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL15100127 | 0.93 | ITGB3 (0.56) | ITGB1ITGA4ITGB3ITGA2BPPARG | |
| SCHEMBL22449263 | 0.93 | ITGB3 (0.56) | ITGB1ITGA4ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |