Styrene

Styrene

SCHEMBL2244944

C=C(C)C=CS(=O)(=O)O.C=Cc1ccccc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TSHR P16473 3/20 0.47
TDP1 Q9NUW8 3/20 0.42
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.35
AKR1C3 P42330 1/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 1/20 0.34
HDAC8 Q9BY41 2/20 0.33
HTT P42858 1/20 0.33
ALOX15 P16050 1/20 0.33
TTR P02766 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HDAC3 O15379 1/20 0.32
TNKS O95271 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4262472 0.98 ALDH1A1 (0.45) ALDH1A1TSHRTDP1GLACYP3A4
Styrene SCHEMBL8365209 0.97 ALDH1A1 (0.44) ALDH1A1TSHRTDP1GLACYP3A4
Styrene SCHEMBL11054146 0.83 ALDH1A1 (0.42) ALDH1A1TSHRTDP1GLACYP3A4
Styrene SCHEMBL29042470 0.82 ALDH1A1 (0.64) ALDH1A1TSHRTDP1GLACYP3A4
Styrene SCHEMBL7711611 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTDP1GLACYP3A4
Styrene SCHEMBL210091 0.79 TSHR (0.54) ALDH1A1TSHRTDP1MAPTKMT2A
SCHEMBL20474516 0.78 HTT (0.43) ALDH1A1TDP1GLACYP3A4MAPT
SCHEMBL10777428 0.78 HTT (0.43) ALDH1A1TDP1GLACYP3A4MAPT
Styrene SCHEMBL1396668 0.78 ALDH1A1 (0.64) ALDH1A1TSHRTDP1GLAAKR1C3
Styrene SCHEMBL8531266 0.78 ALDH1A1 (0.64) ALDH1A1TSHRTDP1MAPTHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639241-A1 ENCAPSULATED BREAKER CHEMICAL EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-02-22 EP claimed
EP-0585228-A4 ENCAPSULATED BREAKER CHEMICAL WITH A MULTI-COAT LAYER UREA EXXON RESEARCH ENGINEERING CO (US) 1994-05-18 EP claimed
EP-0586383-A4 BREAKER CHEMICAL ENCAPSULATED WITH A CROSSLINKED ELASTOMER COATING EXXON RESEARCH ENGINEERING CO (US) 1994-05-18 EP claimed
EP-0639241-A4 ENCAPSULATED BREAKER CHEMICAL. EXXON RESEARCH ENGINEERING CO (US) 1994-03-31 EP claimed
EP-0586383-A1 BREAKER CHEMICAL ENCAPSULATED WITH A CROSSLINKED ELASTOMER COATING EXXON RESEARCH AND ENGINEERING COMPANY (US) 1994-03-16 EP claimed
EP-0585228-A1 ENCAPSULATED BREAKER CHEMICAL WITH A MULTI-COAT LAYER UREA EXXON RESEARCH AND ENGINEERING COMPANY (US) 1994-03-09 EP claimed
WO-1992017683-A1 BREAKER CHEMICAL ENCAPSULATED WITH A CROSSLINKED ELASTOMER COATING EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-10-15 WO claimed
WO-1992012327-A1 ENCAPSULATED BREAKER CHEMICAL EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-07-23 WO claimed
WO-1992012328-A1 ENCAPSULATED BREAKER CHEMICAL WITH A MULTI-COAT LAYER UREA EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-07-23 WO claimed
US-5110486-A Neutralized sulfonated elastomeric copolymer; sustained release EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-05-05 US claimed
US-5102558-A Neutralized sulfonated elastomers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-04-07 US claimed
US-5102559-A Particulate breaker composition sealed with a water soluble layer and coated with a neutralized sulfonated elastomeric polymer for fracturing subterranean formations EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-04-07 US claimed
US-10837192-B2 Seismic isolation systems comprising a load-bearing surface having a polymeric material WORKSAFE TECHNOLOGIES (US) 2020-11-17 US disclosed
US-9856414-B2 Compositions, systems and methods of making coated additive components DOBER CHEMICAL CORP. (US) 2018-01-02 US disclosed
US-20170350152-A1 SEISMIC ISOLATION SYSTEMS COMPRISING A LOAD-BEARING SURFACE HAVING A POLYMERIC MATERIAL WORKSAFE TECHNOLOGIES 2017-12-07 US disclosed
US-9070399-B2 Polishing liquid composition for magnetic-disk substrate KAO CORPORATION (JP) 2015-06-30 US disclosed
WO-1992012327-A1 ENCAPSULATED BREAKER CHEMICAL EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-07-23 WO disclosed
US-5110486-A Neutralized sulfonated elastomeric copolymer; sustained release EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-05-05 US disclosed
US-5102558-A Neutralized sulfonated elastomers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-04-07 US disclosed
US-5102559-A Particulate breaker composition sealed with a water soluble layer and coated with a neutralized sulfonated elastomeric polymer for fracturing subterranean formations EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-04-07 US disclosed