Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466542 | 0.80 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL21001982 | 0.78 | ALDH1A1 (0.62) | GAASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL5697246 | 0.75 | ALDH1A1 (0.68) | GAASMN1; SMN2ALDH1A1CHRNA7HTR3A | |
| SCHEMBL25318734 | 0.74 | PIK3CD (0.35) | SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL2678410 | 0.74 | SMN1; SMN2 (0.51) | GAASMN1; SMN2ALDH1A1CHRNA7HTR3A | |
| SCHEMBL5639167 | 0.74 | ALDH1A1 (0.43) | GAASMN1; SMN2ALDH1A1CHRNA7HTR3A | |
| SCHEMBL5639158 | 0.74 | ALDH1A1 (0.43) | GAASMN1; SMN2ALDH1A1CHRNA7HTR3A | |
| SCHEMBL22449981 | 0.73 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL20553753 | 0.73 | SMN1; SMN2 (0.50) | GAASMN1; SMN2ALDH1A1CHRNA7HTR3A | |
| SCHEMBL25323472 | 0.73 | PDE4A (0.43) | ALDH1A1KDM4ENPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712140-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | California Institute of Technology (US) | 2020-09-23 | — | — | EP | disclosed |