Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834895 | 0.81 | HSD11B1 (0.60) | HSD11B1DDB1CRBNALDH1A1ROCK2 | |
| SCHEMBL6734403 | 0.81 | HSD11B1 (0.56) | HSD11B1DDB1CRBNALDH1A1ROCK2 | |
| SCHEMBL6732065 | 0.79 | HSD11B1 (0.55) | HSD11B1DDB1CRBNALDH1A1KMT2A | |
| SCHEMBL22450119 | 0.76 | HSD11B1 (0.51) | HSD11B1ALDH1A1SIGMAR1F2 | |
| SCHEMBL3125721 | 0.75 | HSD11B1 (0.50) | HSD11B1KMT2AF2 | |
| SCHEMBL28942364 | 0.73 | HSD11B1 (0.59) | HSD11B1DDB1CRBNALDH1A1ROCK2 | |
| SCHEMBL5106732 | 0.73 | HSD11B1 (0.59) | HSD11B1DDB1CRBNALDH1A1ROCK2 | |
| SCHEMBL5088875 | 0.73 | HSD11B1 (0.59) | HSD11B1DDB1CRBNALDH1A1ROCK2 | |
| SCHEMBL19050135 | 0.73 | DDB1 (0.51) | HSD11B1DDB1CRBNALDH1A1F2 | |
| SCHEMBL8676314 | 0.73 | DDB1 (0.51) | HSD11B1DDB1CRBNALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712140-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | California Institute of Technology (US) | 2020-09-23 | — | — | EP | disclosed |