Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23714070 | 0.83 | CYP1A2 (0.47) | KMT2AKDM4EMMP2PIM1CYP1A2 | |
| SCHEMBL22451969 | 0.82 | CYP1A2 (0.41) | KMT2AKDM4EPIM1CYP1A2HPGDS | |
| SCHEMBL24454416 | 0.81 | KDM4E (0.38) | KMT2AKDM4EMMP2PIM1CYP1A2 | |
| SCHEMBL32315381 | 0.79 | P2RX7 (0.50) | KMT2AKDM4ECYP1A2ALDH1A1HPGDS | |
| SCHEMBL946380 | 0.79 | P2RX7 (0.50) | KMT2AKDM4ECYP1A2ALDH1A1HPGDS | |
| SCHEMBL1424052 | 0.77 | KDM4E (0.66) | KMT2AKDM4EMMP2PIM1PFKFB3 | |
| SCHEMBL4312684 | 0.76 | MGAM (0.56) | KMT2AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6986429 | 0.76 | MCHR1 (0.39) | KMT2APIM1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6984222 | 0.75 | CYP1A2 (0.41) | KDM4EMMP2PIM1CYP1A2ALDH1A1 | |
| SCHEMBL15724450 | 0.75 | GRM6 (0.46) | KMT2AKDM4EATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020186328-A1 | CHELATORS AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-09-24 | — | — | WO | disclosed |