Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013130 | 0.83 | TP53 (0.44) | ESR1LMNAMAPTTSHRTP53 | |
| SCHEMBL10799818 | 0.82 | ESR1 (0.44) | ESR1S1PR1RAB9ALMNAC5AR1 | |
| SCHEMBL9555105 | 0.81 | TP53 (0.43) | ESR1LMNAMAPTTSHRTP53 | |
| SCHEMBL6302958 | 0.78 | ESR1 (0.46) | ESR1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL9347228 | 0.76 | ESR1 (0.44) | ESR1LMNATSHRTP53ALDH1A1 | |
| SCHEMBL5367358 | 0.76 | TAAR1 (0.42) | ESR1S1PR1RAB9ALMNAC5AR1 | |
| SCHEMBL6310444 | 0.74 | TP53 (0.41) | ESR1LMNAMAPTTSHRTP53 | |
| SCHEMBL11788444 | 0.74 | S1PR1 (0.38) | ESR1S1PR1LMNATSHRTP53 | |
| SCHEMBL8615002 | 0.73 | ESR1 (0.40) | ESR1S1PR1LMNATSHRTP53 | |
| SCHEMBL18537812 | 0.72 | MEN1 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470242-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1230381-A4 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH INC (US) | 2004-10-13 | — | — | EP | claimed |
| US-6664073-B1 | Contacting with cystathionine beta-synthase, L-serine, and cystathionine beta-lyase to catalyze the cyclical conversion of homocysteine to cystathionine and the reconversion of cystathionine to homocysteine; pyruvate and NH3 | CATCH INC. | 2003-12-16 | — | — | US | claimed |
| US-6635438-B2 | Beta-synthase, L-serine, cystathionine beta-lyase; amount of pyruvate and/or ammonia produced from reconversion of cystathionine to homocysteine; improvement comprises completing the enzymatic conversion in less than 15 minutes | CATCH, INC. | 2003-10-21 | — | — | US | claimed |
| US-20030138872-A1 | Enzymatic cycling assays for homocysteine and cystathionine | AXIS-SHIELD DIAGNOSTICS, LTD. (GB) | 2003-07-24 | — | — | US | claimed |
| WO-2003040694-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| EP-1230381-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001033187-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2001-05-10 | — | — | WO | claimed |
| EP-1470242-B1 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | AXIS SHIELD DIAGNOSTICS LTD (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-1230381-B1 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | AXIS SHIELD DIAGNOSTICS LTD (GB) | 2011-07-27 | — | — | EP | disclosed |
| US-6867014-B2 | Enzymatic cycling assays for homocysteine and cystathionine | CATCH, INC. | 2005-03-15 | — | — | US | disclosed |
| EP-1470242-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040096929-A1 | Enzymatic cycling assays for homocysteine and cystathionine | AXIS-SHIELD DIAGNOSTICS, LTD. (GB) | 2004-05-20 | — | — | US | disclosed |
| US-6664073-B1 | Contacting with cystathionine beta-synthase, L-serine, and cystathionine beta-lyase to catalyze the cyclical conversion of homocysteine to cystathionine and the reconversion of cystathionine to homocysteine; pyruvate and NH3 | CATCH INC. | 2003-12-16 | — | — | US | disclosed |
| US-6635438-B2 | Beta-synthase, L-serine, cystathionine beta-lyase; amount of pyruvate and/or ammonia produced from reconversion of cystathionine to homocysteine; improvement comprises completing the enzymatic conversion in less than 15 minutes | CATCH, INC. | 2003-10-21 | — | — | US | disclosed |
| US-20030138872-A1 | Enzymatic cycling assays for homocysteine and cystathionine | AXIS-SHIELD DIAGNOSTICS, LTD. (GB) | 2003-07-24 | — | — | US | disclosed |
| WO-2003040694-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2003-05-15 | — | — | WO | disclosed |