Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 2/20 | 0.32 |
| ▸ | ELOC | Q15369 | 2/20 | 0.32 |
| ▸ | ELOB | Q15370 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24502762 | 0.97 | TTR (0.36) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL26284929 | 0.95 | TTR (0.37) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL24450048 | 0.93 | TTR (0.36) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL22459214 | 0.93 | KLKB1 (0.33) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL26286101 | 0.93 | TTR (0.37) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL20016562 | 0.92 | TTR (0.45) | TTRIL2KLKB1PLGFOLH1 | |
| SCHEMBL25052808 | 0.90 | TTR (0.37) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL24335147 | 0.88 | TTR (0.43) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL26412265 | 0.88 | TTR (0.42) | TTRIL2KLKB1PLGVHL | |
| SCHEMBL22388613 | 0.87 | KLKB1 (0.37) | TTRIL2KLKB1PLGFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107560-A1 | DLK1 ANTIBODIES AND METHODS OF TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107558-A1 | CDH17 ANTIBODIES AND METHODS OF TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2020191344-A1 | CLAUDIN-6 BISPECIFIC ANTIBODIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020191342-A1 | CLAUDIN-6 ANTIBODIES AND DRUG CONJUGATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | disclosed |