SCHEMBL26412265

SCHEMBL26412265

CC(C)(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCOCCCOCCn2cc(CNC(=O)C3CCC(CN4C(=O)C=CC4=O)CC3)nn2)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.42
▸ IL2 P60568 1/20 0.42
▸ KLKB1 P03952 3/20 0.36
▸ FOLH1 Q04609 1/20 0.34
▸ PLG P00747 1/20 0.33
▸ OPRM1 P35372 1/20 0.32
▸ VHL P40337 2/20 0.31
▸ ELOC Q15369 2/20 0.31
▸ ELOB Q15370 2/20 0.31
▸ F2RL1 P55085 1/20 0.31
▸ F2R P25116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24335147 0.99 TTR (0.43) TTRIL2KLKB1FOLH1PLG
SCHEMBL20016562 0.93 TTR (0.45) TTRIL2KLKB1FOLH1PLG
SCHEMBL26286101 0.92 TTR (0.37) TTRIL2KLKB1FOLH1PLG
SCHEMBL25052808 0.92 TTR (0.37) TTRIL2KLKB1FOLH1PLG
SCHEMBL29351004 0.91 TTR (0.46) TTRIL2KLKB1FOLH1PLG
SCHEMBL25204552 0.89 TTR (0.46) TTRIL2KLKB1FOLH1PLG
SCHEMBL22452311 0.88 TTR (0.37) TTRIL2KLKB1FOLH1PLG
SCHEMBL26284929 0.88 TTR (0.37) TTRIL2KLKB1FOLH1PLG
SCHEMBL24176337 0.87 TTR (0.37) TTRIL2KLKB1FOLH1PLG
SCHEMBL12342504 0.86 TTR (0.44) TTRIL2KLKB1FOLH1PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230126689-A1 ANTI-GLYCO-CD44 ANTIBODIES AND THEIR USES GO THERAPEUTICS, INC. (US) 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230126689-A1 ANTI-GLYCO-CD44 ANTIBODIES AND THEIR USES CD44, SIGLEC7, SIGLEC9 TTR 2552/4885IL2 3138/4885KLKB1 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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