Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22443656 | 0.78 | GBA1 (0.38) | ALDH1A1SIGMAR1OPRK1OPRL1 | |
| SCHEMBL22443654 | 0.78 | GBA1 (0.38) | ALDH1A1SIGMAR1OPRK1OPRL1 | |
| SCHEMBL22443391 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AACHESIGMAR1 | |
| SCHEMBL22443392 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AACHESIGMAR1 | |
| SCHEMBL22443488 | 0.72 | GRIN2B (0.40) | ALDH1A1MEN1KMT2ASIGMAR1GRIN2B | |
| SCHEMBL22443570 | 0.72 | GRIN2B (0.40) | ALDH1A1MEN1KMT2ASIGMAR1GRIN2B | |
| SCHEMBL22443486 | 0.72 | GRIN2B (0.40) | ALDH1A1MEN1KMT2ASIGMAR1GRIN2B | |
| SCHEMBL22443564 | 0.72 | GRIN2B (0.40) | ALDH1A1MEN1KMT2ASIGMAR1GRIN2B | |
| SCHEMBL21441827 | 0.66 | GBA1 (0.41) | ACHESIGMAR1OPRK1OPRL1 | |
| SCHEMBL17979137 | 0.66 | GBA1 (0.41) | ACHESIGMAR1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020188301-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2020-09-24 | — | — | WO | disclosed |