SCHEMBL22452853

SCHEMBL22452853

CC(=O)[C@H]1CCC(C)(C)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711237 0.82 CYP2D6 (0.39)
SCHEMBL711236 0.82 CYP2D6 (0.39)
SCHEMBL26431133 0.82
SCHEMBL19222961 0.80 GLI1 (0.36)
SCHEMBL17190116 0.80 GLI1 (0.36)
Hydrochloric Acid SCHEMBL28515120 0.80 CYP2D6 (0.37)
SCHEMBL28156474 0.80
Hydrochloric Acid SCHEMBL28515119 0.80 CYP2D6 (0.37)
Hydrochloric Acid SCHEMBL15776210 0.78 GLI1 (0.35)
SCHEMBL23644218 0.77 KMT2A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020188301-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2020-09-24 WO disclosed