SCHEMBL711236

SCHEMBL711236

CC1(C)CCC(C(=O)O)N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.39
LMNA P02545 3/20 0.39
BLM P54132 3/20 0.39
ALOX15 P16050 3/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2C19 P33261 3/20 0.39
RAB9A P51151 2/20 0.39
PMP22 Q01453 2/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
KMT2A Q03164 1/20 0.39
HTT P42858 1/20 0.36
GRM2 Q14416 1/20 0.35
GRM3 Q14832 1/20 0.35
APLNR P35414 1/20 0.34
MAPK1 P28482 3/20 0.34
MAPT P10636 1/20 0.34
SLC1A2 P43004 2/20 0.33
SLC1A1 P43005 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711237 1.00 CYP2D6 (0.39) CYP2D6LMNABLMALOX15CYP1A2
Hydrochloric Acid SCHEMBL28515119 0.98 CYP2D6 (0.37) CYP2D6LMNABLMALOX15CYP1A2
Hydrochloric Acid SCHEMBL28515120 0.98 CYP2D6 (0.37) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL28626348 0.87 CYP1A2 (0.36) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL26431133 0.82
SCHEMBL22452853 0.82
SCHEMBL19222961 0.80 GLI1 (0.36) SMN1; SMN2
SCHEMBL13430608 0.80 CYP2D6 (0.37) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL17190116 0.80 GLI1 (0.36) SMN1; SMN2
SCHEMBL28156474 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570697-B2 Cyclic peptide useful in the treatment of cancer SYNTHERIX LIMITED (GB) 2026-03-10 US claimed
EP-3947418-B1 PEPTIDES AND USE THEREOF SYNTHERIX LTD (GB) 2024-04-03 EP claimed
US-20220242914-A1 PEPTIDES AND USE THEREOF SYNTHERIX LIMITED (GB) 2022-08-04 US claimed
EP-3947418-A2 PEPTIDES AND USE THEREOF Warenius, Hilmar M (GB) 2022-02-09 EP claimed
WO-2020193978-A2 PEPTIDES AND USE THEREOF WARENIUS HILMAR (GB) 2020-10-01 WO claimed
US-12570697-B2 Cyclic peptide useful in the treatment of cancer SYNTHERIX LIMITED (GB) 2026-03-10 US disclosed
US-12570697-B2 Cyclic peptide useful in the treatment of cancer SYNTHERIX LIMITED (GB) 2026-03-10 US disclosed
WO-2025081231-A1 INHIBITORS AND USES THEREFOR Infensa Bioscience Pty Ltd (AU) 2025-04-24 WO disclosed
US-20240344241-A1 PROTEINACEOUS MOLECULES AND USES THEREFOR THE UNIVERSITY OF TOKYO (JP) 2024-10-17 US disclosed
EP-4416282-A1 PROTEINACEOUS MOLECULES AND USES THEREFOR The University of Queensland (AU) 2024-08-21 EP disclosed
EP-3947418-B1 PEPTIDES AND USE THEREOF SYNTHERIX LTD (GB) 2024-04-03 EP disclosed
US-11872262-B2 Means and methods for treating bacterial infections VIB VZW (BE) 2024-01-16 US disclosed
WO-2007093012-A1 CONOTOXIN ANALOGUES, AND METHODS FOR SYNTHESIS OF INTRAMOLECULAR DICARBA BRIDGE CONTAINING PEPTIDES MONASH UNIVERSITY (AU) 2007-08-23 WO disclosed
WO-2006127702-A2 ANALOGS OF GLYCYL-PROLYL-GLUTAMATE NEUREN PHARMACEUTICALS LIMITED (NZ) 2006-11-30 WO disclosed
WO-2006089311-A1 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS AMGEN INC. (US) 2006-08-24 WO disclosed
US-20060183745-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2006-08-17 US disclosed
US-4977260-A Intermediates for preparing mono-, bi- and tricyclic amino acids HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-11 US disclosed
US-4849524-A Process of preparing proline derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-18 US disclosed
US-4691022-A Process for the preparation of monocyclic, bicyclic and tricyclic aminoacids HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-01 US disclosed
EP-0132580-A1 Process for the preparation of mono, bi and tricyclic aminoacids HOECHST AKTIENGESELLSCHAFT (DE) 1985-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183745-A1 Vanilloid receptor ligands and their use in treatments TRPV1, TRPV2, TRPV3 CYP2D6 2008/4885LMNA 3908/4885BLM 2266/4885
US-12570697-B2 Cyclic peptide useful in the treatment of cancer NPR1, NPR3, PTMS CYP2D6 1778/4885LMNA 716/4885BLM 2026/4885
US-11872262-B2 Means and methods for treating bacterial infections VIP, MMP8, SLC11A2 CYP2D6 4718/4885LMNA 3795/4885BLM 1975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.