Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.41 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452953 | 0.93 | TUBB4A (0.44) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22453290 | 0.90 | AKR1C3 (0.48) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22453050 | 0.90 | MEN1 (0.46) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22452476 | 0.88 | MEN1 (0.60) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22453330 | 0.87 | KDM4C (0.47) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22452450 | 0.85 | MEN1 (0.46) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22453439 | 0.83 | TUBB4A (0.46) | LMNAMAPTDHODHSMN1; SMN2AKR1C3 | |
| SCHEMBL22452452 | 0.83 | DHODH (0.47) | KDM4CKDM6BDHODHKCNK2IGF2BP2 | |
| SCHEMBL22452951 | 0.82 | TUBB4A (0.44) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22453590 | 0.81 | MEN1 (0.49) | MEN1LMNAKMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |