Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546720 | 0.89 | CYP1A2 (0.64) | CYP1A2SLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL22453534 | 0.86 | CYP1A2 (0.59) | CYP1A2SLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL22453335 | 0.78 | CYP1A2 (0.46) | CYP1A2SLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL22453580 | 0.76 | DHODH (0.50) | CYP1A2SLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL22453362 | 0.76 | CYP1A2 (0.47) | CYP1A2SLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL22452559 | 0.76 | CNR2 (0.43) | CYP1A2SLC2A1MEN1KMT2ANPC1 | |
| SCHEMBL21708010 | 0.76 | GAA (0.64) | CYP1A2MEN1KMT2ANPC1MAPT | |
| SCHEMBL2832191 | 0.76 | CYP1A2 (0.86) | CYP1A2KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL22453116 | 0.76 | HIF1A (0.47) | CYP1A2SLC2A1NPC1MAPTALDH1A1 | |
| SCHEMBL1478915 | 0.75 | CYP1A2 (1.00) | CYP1A2MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |