Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452463 | 0.90 | DHODH (0.46) | MAPTPNLIPALDH1A1KMT2A | |
| SCHEMBL22453594 | 0.89 | MEN1 (0.47) | MAPTPNLIPKDM4EALDH1A1HPGD | |
| SCHEMBL22453400 | 0.86 | DHODH (0.46) | MAPTALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL22452475 | 0.83 | MEN1 (0.58) | MAPTPNLIPHPGDPOLBKMT2A | |
| SCHEMBL22453390 | 0.78 | DHODH (0.42) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22453592 | 0.78 | MRGPRX4 (0.53) | MAPTALOX15PNLIPKDM4EKMT2A | |
| SCHEMBL22452646 | 0.77 | SERPINE1 (0.50) | MAPTALOX15KDM4EALDH1A1HPGD | |
| SCHEMBL22453205 | 0.77 | MAPT (0.46) | MAPTALOX15PNLIPGCGR | |
| SCHEMBL22452663 | 0.76 | DHODH (0.54) | GRM4POLBKMT2A | |
| SCHEMBL27232464 | 0.76 | MAPT (0.55) | MAPTPNLIPALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |