Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453840 | 0.91 | VEGFA (0.43) | VEGFAEGLN1SIGMAR1ADRA2AHTR2A | |
| SCHEMBL22444151 | 0.81 | SIGMAR1 (0.42) | SIGMAR1ACHEMEN1KMT2AGAA | |
| SCHEMBL22444194 | 0.81 | SIGMAR1 (0.42) | SIGMAR1ACHEMEN1KMT2AGAA | |
| SCHEMBL22453820 | 0.80 | VEGFA (0.37) | VEGFAEGLN1SIGMAR1ADRA2AHTR2A | |
| SCHEMBL22443700 | 0.80 | TOP2A (0.36) | SIGMAR1ADRA2AHTR2AACHEGAA | |
| SCHEMBL22443698 | 0.80 | TOP2A (0.36) | SIGMAR1ADRA2AHTR2AACHEGAA | |
| SCHEMBL22453308 | 0.78 | VEGFA (0.38) | VEGFAEGLN1SIGMAR1ADRA2AHTR2A | |
| SCHEMBL22443666 | 0.75 | GAA (0.41) | SIGMAR1ACHEGAA | |
| SCHEMBL22443667 | 0.75 | GAA (0.41) | SIGMAR1ACHEGAA | |
| SCHEMBL22443677 | 0.75 | GAA (0.41) | SIGMAR1ACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020188301-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2020-09-24 | — | — | WO | disclosed |