SCHEMBL22454077

SCHEMBL22454077

C=CC(=O)OCC(COc1ccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)cc1)OC

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
PDE4D Q08499 4/20 0.34
TSHR P16473 2/20 0.33
CYP2C9 P11712 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
POLB P06746 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PDK2 Q15119 2/20 0.31
TP53 P04637 2/20 0.31
MDM2 Q00987 2/20 0.31
CNR1 P21554 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22596746 0.93 CYP2C9 (0.41) THRBTSHRCYP2C9KMT2APOLB
SCHEMBL732791 0.90 AR (0.39) THRBTSHRCYP2C9KMT2AMEN1
SCHEMBL21616027 0.88 THRB (0.34) THRBTSHRKMT2AMEN1POLB
SCHEMBL21237534 0.87 THRB (0.33) THRBTSHRKMT2AMEN1POLB
SCHEMBL14375161 0.87 THRB (0.39) THRBKMT2AMEN1POLBLMNA
SCHEMBL16425356 0.86 THRB (0.40) THRBTSHRKMT2AMEN1POLB
SCHEMBL23808371 0.84 POLB (0.35) THRBKMT2AMEN1POLBKDM4E
SCHEMBL16425354 0.83 THRB (0.36) THRBTSHRKMT2AMEN1POLB
SCHEMBL22040657 0.82 THRB (0.34) THRBTSHRCYP2C9KMT2APOLB
SCHEMBL2619381 0.82 POLB (0.33) THRBTSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163634-A1 CURABLE COMPOSITION, CURED FILM, INFRARED TRANSMITTING FILTER, LAMINATE, SOLID-STATE IMAGING ELEMENT, SENSOR, AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2021-06-03 US disclosed
US-20210102010-A1 CURABLE COMPOSITION, FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, INFRARED SENSOR, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2021-04-08 US disclosed
US-20200341374-A1 PHOTOSENSITIVE COMPOSITION FUJIFILM CORPORATION (JP) 2020-10-29 US disclosed
US-20200301272-A1 CURABLE COMPOSITION, NEAR INFRARED ABSORBER, FILM, NEAR INFRARED CUT FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND INFRARED SENSOR FUJIFILM CORPORATION (JP) 2020-09-24 US disclosed
US-20200299512-A1 COMPOSITION, FILM, INFRARED TRANSMITTING FILTER, AND SOLID-STATE IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2020-09-24 US disclosed