Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741622 | 0.87 | HPGD (0.43) | HPGDTDP1KDM4ERAB9ANPC1 | |
| SCHEMBL22454839 | 0.87 | HPGD (0.43) | HPGDTDP1KDM4ERAB9ANPC1 | |
| SCHEMBL24199697 | 0.87 | TDP1 (0.57) | TDP1RAB9ANPC1TP53ATM | |
| SCHEMBL30854477 | 0.82 | MEN1 (0.42) | HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30928883 | 0.82 | MEN1 (0.42) | HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28741490 | 0.81 | HPGD (0.39) | HPGDTDP1KDM4ERAB9ANPC1 | |
| SCHEMBL22444866 | 0.80 | TPH1 (0.44) | HPGDTDP1KDM4EALDH1A1 | |
| SCHEMBL22444585 | 0.79 | ITGB1 (0.45) | HPGDKDM4E | |
| SCHEMBL29633723 | 0.79 | HPGD (0.39) | HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22444695 | 0.77 | ITGB1 (0.40) | HPGDKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939962-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |