Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTCH1 | P46531 | 19/20 | 0.40 |
| ▸ | RBPJ | Q06330 | 9/20 | 0.40 |
| ▸ | NOTCH3 | Q9UM47 | 10/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22455447 | 0.77 | NOTCH1 (0.38) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL22440656 | 0.76 | CCKBR (0.43) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL22440657 | 0.76 | CCKBR (0.43) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL22455437 | 0.74 | CCKBR (0.48) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL22459818 | 0.72 | NOTCH1 (0.37) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL22440655 | 0.69 | NOTCH1 (0.38) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL18167317 | 0.68 | NOTCH1 (0.56) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL27100116 | 0.67 | NOTCH1 (0.36) | NOTCH1RBPJNOTCH3CCKBR | |
| SCHEMBL22455408 | 0.67 | NOTCH1 (0.36) | NOTCH1RBPJNOTCH3CCKARCCKBR | |
| SCHEMBL22460059 | 0.67 | NOTCH1 (0.38) | NOTCH1RBPJNOTCH3CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190935-A1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |