Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435767 | 0.77 | JAK2 (0.42) | BDKRB1JAK2BRD4 | |
| SCHEMBL17131615 | 0.73 | — | — | |
| SCHEMBL17131659 | 0.73 | — | — | |
| SCHEMBL17131626 | 0.73 | — | — | |
| SCHEMBL4701138 | 0.71 | EPHX1 (0.39) | GRIA4GRIA2 | |
| SCHEMBL17132890 | 0.70 | — | — | |
| SCHEMBL4368033 | 0.70 | — | — | |
| SCHEMBL17125421 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL998147 | 0.69 | EPHX1 (0.38) | GRIA4GRIA2 | |
| SCHEMBL26145142 | 0.69 | GRIA4 (0.35) | GRIA4GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191205-A1 | PI4-KINASE INHIBITORS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-09-24 | — | — | WO | disclosed |