Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PRF1 | P14222 | 4/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22456743 | 0.95 | CHEK1 (0.38) | CHEK1ADORA2AKMT2AMEN1ATM | |
| SCHEMBL22456754 | 0.95 | ADORA2A (0.39) | CHEK1ADORA2AKMT2AMEN1ATM | |
| SCHEMBL22456740 | 0.93 | ADORA2A (0.38) | CHEK1ADORA2AKMT2AMEN1ATM | |
| SCHEMBL22456755 | 0.92 | ADORA2A (0.41) | CHEK1ADORA2AKMT2AMEN1ATM | |
| SCHEMBL22456809 | 0.89 | ALDH1A1 (0.42) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL22456753 | 0.85 | PTGER4 (0.37) | CHEK1ADORA2AKMT2AMEN1ATM | |
| SCHEMBL22456454 | 0.84 | ALDH1A1 (0.41) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL22456456 | 0.83 | ALDH1A1 (0.46) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL22456496 | 0.83 | ALDH1A1 (0.46) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL22456805 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200303661-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200303661-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | NR2E3, NR2E1, NOX1 | CHEK1 1251/4885ADORA2A 1858/4885KMT2A 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.