Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22459582 | 0.94 | ABCB1 (0.54) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22459984 | 0.90 | MAPT (0.61) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27350540 | 0.85 | ABCB1 (0.71) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22460005 | 0.78 | MEN1 (0.70) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22459378 | 0.77 | MAPT (0.65) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20534814 | 0.77 | MEN1 (0.54) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20534813 | 0.76 | MAPT (0.64) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20535339 | 0.76 | MAPT (0.67) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22459583 | 0.76 | MEN1 (0.69) | ABCB1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22812901 | 0.74 | MEN1 (0.64) | MEN1KMT2AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110105-B2 | Compounds, composition and uses thereof for treating cancer | INSTITUT GUSTAVE ROUSSY (FR) | 2021-09-07 | — | — | US | disclosed |
| US-20200297741-A1 | COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200297741-A1 | COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER | PTPRC, PTPRS, PTPRCAP | ABCB1 1217/4885MEN1 2190/4885KMT2A 3703/4885 |
| US-11110105-B2 | Compounds, composition and uses thereof for treating cancer | PTPRC, PTPRS, PTPRCAP | ABCB1 1217/4885MEN1 2190/4885KMT2A 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.