Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HBB | P68871 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 2/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | FLT3 | P36888 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22459378 | 0.96 | MAPT (0.65) | MEN1MAPTKMT2AUSP2TP53 | |
| SCHEMBL20534813 | 0.95 | MAPT (0.64) | MEN1MAPTKMT2AUSP2TP53 | |
| Kayaflavone SCHEMBL30646162 | 0.92 | MEN1 (0.71) | MEN1MAPTKMT2AUSP2TP53 | |
| Kayaflavone SCHEMBL27350697 | 0.92 | MEN1 (0.71) | MEN1MAPTKMT2AUSP2TP53 | |
| SCHEMBL28365603 | 0.91 | MAPT (0.64) | MEN1MAPTKMT2AUSP2TP53 | |
| Isoginkgetin SCHEMBL22459983 | 0.89 | MEN1 (0.80) | MEN1MAPTKMT2AUSP2TP53 | |
| Isoginkgetin SCHEMBL30293900 | 0.89 | MEN1 (0.80) | MEN1MAPTKMT2AUSP2TP53 | |
| SCHEMBL22459584 | 0.89 | MAPT (0.77) | MEN1MAPTKMT2AUSP2TP53 | |
| SCHEMBL20535339 | 0.88 | MAPT (0.67) | MEN1MAPTKMT2AUSP2TP53 | |
| 7'',4'''-Dimethylamentoflavone SCHEMBL30646161 | 0.87 | APP (0.72) | MEN1MAPTKMT2AUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609878-B1 | COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER | ROUSSY INST GUSTAVE (FR) | 2020-12-23 | — | — | EP | disclosed |