Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 6/20 | 1.00 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.73 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.64 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.64 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22465348 | 0.90 | CACNA1H (1.00) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| Cudraflavanone B SCHEMBL23140484 | 0.88 | CACNA1H (0.79) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL22465767 | 0.88 | CACNA1H (0.79) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL1171132 | 0.88 | CACNA1H (0.84) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL24075694 | 0.88 | CACNA1H (0.84) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL22465747 | 0.87 | CACNA1H (0.77) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL145714 | 0.84 | CACNA1H (1.00) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL22465607 | 0.84 | CACNA1H (1.00) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL145713 | 0.84 | CACNA1H (1.00) | CACNA1HSOAT2CACNA1GESR1MAPT | |
| SCHEMBL29394512 | 0.84 | CACNA1H (1.00) | CACNA1HSOAT2CACNA1GESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479537-B2 | T-type calcium channel inhibitor | KINKI UNIVERSITY (JP) | 2022-10-25 | — | — | US | claimed |
| US-20200308132-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA (JP) | 2020-10-01 | — | — | US | claimed |
| US-11479537-B2 | T-type calcium channel inhibitor | KINKI UNIVERSITY (JP) | 2022-10-25 | — | — | US | disclosed |
| US-20200308132-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA (JP) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11479537-B2 | T-type calcium channel inhibitor | CACNA1H, CACNA1I, CACNA1G | CACNA1H 1/4885SOAT2 2503/4885CACNA1G 3/4885 |
| US-20200308132-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | CACNA1H, CACNA1I, CACNA1G | CACNA1H 1/4885SOAT2 2503/4885CACNA1G 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.