⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358818 | 0.79 | — | — | |
| SCHEMBL1149488 | 0.78 | — | — | |
| SCHEMBL7202962 | 0.73 | — | — | |
| SCHEMBL1290618 | 0.64 | — | — | |
| SCHEMBL2172258 | 0.61 | — | — | |
| SCHEMBL63347 | 0.61 | — | — | |
| SCHEMBL123364 | 0.61 | — | — | |
| SCHEMBL31364181 | 0.61 | FDPS (0.50) | — | |
| SCHEMBL992305 | 0.59 | ALPG (0.31) | — | |
| SCHEMBL277895 | 0.59 | ALPG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999960-B2 | Oxidized thiophospholipid compounds and uses thereof | VASCULAR BIOGENICS LTD. (IL) | 2015-04-07 | — | — | US | claimed |
| US-20110195937-A1 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-08-11 | — | — | US | claimed |
| EP-2348864-A2 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | claimed |
| WO-2010041242-A2 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-04-15 | — | — | WO | claimed |
| CN-115947758-A | Nucleotide derivative and pharmaceutical composition and application thereof | 南京知和医药科技有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-20230002424-A1 | PROCESS FOR PREPARATION OF THIOPHOSPHORYL CHLORIDE AND ACEPHATE | UPL LTD (IN) | 2023-01-05 | — | — | US | disclosed |
| CN-115477696-A | Albumin active polypeptide powder for improving hypodynamia symptoms and preparation method thereof | 杭州佰倍优生物科技有限公司 | 2022-12-16 | — | — | CN | disclosed |
| EP-3089986-B1 | CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE | RXBIO INC (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20170226139-A1 | CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE | RXBIO INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-9567288-B2 | Crystalline salts of (Z)-O-octadec-9-en-1-yl O,O-dihydrogen phosphorothioate | RXBIO, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| EP-3089986-A1 | CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE | Rxbio Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015102856-A1 | CRYSTALLINE SALTS OF (Z)-O-OCTADEC-9-EN-1-YL O,O-DIHYDROGEN PHOSPHOROTHIOATE | RXBIO INC. (US) | 2015-07-09 | — | — | WO | disclosed |
| EP-0357048-A2 | Process for transhalogenating a halophosphorus compound with hydrogen fluoride | ALBEMARLE CORPORATION (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4904768-A | Epipodophyllotoxin glucoside 4'-phosphate derivatives | BRISTOL-MYERS COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0353598-A2 | Transhalogenation of halophosphorus compounds | ETHYL CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |
| EP-0312790-A2 | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0302473-A2 | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells | Bristol-Myers Squibb Company (US) | 1989-02-08 | — | — | EP | disclosed |
| EP-0234820-A2 | A process for producing 0,0-dilower-alkylchlorothiophosphate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4322414-A | MITICIDES; APHIDICIDES; LARVICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |