Cyclohexane

Cyclohexane

SCHEMBL2246750

C1CCCCC1.C=CC(N)=O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.79
TSHR P16473 4/20 0.79
FGFR4 P22455 1/20 0.79
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 3/20 0.33
OR51E2 Q9H255 1/20 0.33
EPHX1 P07099 1/20 0.32
ACHE P22303 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL346356 1.00 ALDH1A1 (0.79) ALDH1A1TSHRFGFR4LMNATDP1
Acrylamide SCHEMBL1332245 0.89
Acrylamide SCHEMBL170034 0.89 TSHR (1.00) ALDH1A1TSHRFGFR4LMNATDP1
Acrylamide SCHEMBL1332254 0.89
Acrylamide SCHEMBL3051 0.89
Acrylamide SCHEMBL183292 0.89 TSHR (1.00) ALDH1A1TSHRFGFR4LMNATDP1
Acrylamide SCHEMBL8940372 0.85 ALDH1A1 (0.92) ALDH1A1TSHRFGFR4LMNATDP1
Acrylamide SCHEMBL20701874 0.85
Acrylamide SCHEMBL9848722 0.85 ALDH1A1 (0.92) ALDH1A1TSHRFGFR4LMNATDP1
Acrylamide SCHEMBL22412946 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289828-A Polyacrylate, preparation method and use its application 莫门蒂夫性能材料股份有限公司 2018-07-17 CN disclosed
EP-1622575-B1 STICK COMPOSITIONS UNILEVER PLC (GB) 2011-07-27 EP disclosed
US-7347991-B2 combination of gelling agents comprising 1) Ax CO Rx where Ax is an amino acid amide residue, especially glutamic or aspartic acid and Rx is branched alkyl and 2) a different fiber-forming amido structurant; particularly for forming translucent deodorant or antiperspirant sticks UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2008-03-25 US disclosed
EP-1622575-A2 STICK COMPOSITIONS Unilever Plc (GB) 2006-02-08 EP disclosed
WO-2004098553-A2 STICK COMPOSITIONS UNILEVER PLC (GB) 2004-11-18 WO disclosed
US-20040223995-A1 Stick compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040223995-A1 Stick compositions QPCT, F12, ADM2 ALDH1A1 1690/4885TSHR 1264/4885FGFR4 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.