Resveratrol

Resveratrol

SCHEMBL22469907

Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1.[PbH2]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.95
KDM4E B2RXH2 5/20 0.95
TTR P02766 5/20 0.95
LMNA P02545 4/20 0.95
MEN1 O00255 4/20 0.95
MAPT P10636 4/20 0.95
KMT2A Q03164 4/20 0.95
CYP1A1 P04798 4/20 0.95
PTGS2 P35354 4/20 0.95
CYP1B1 Q16678 4/20 0.95
ALOX5 P09917 4/20 0.95
ALDH1A1 P00352 3/20 0.95
TP53 P04637 3/20 0.95
CYP1A2 P05177 3/20 0.95
CYP3A4 P08684 3/20 0.95
CYP2C9 P11712 3/20 0.95
HPGD P15428 3/20 0.95
SMN1; SMN2 Q16637 3/20 0.95
HIF1A Q16665 3/20 0.95
HSD17B10 Q99714 3/20 0.95

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resveratrol SCHEMBL15065503 1.00 PTGS1 (0.95) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL2300985 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL17629801 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL15106855 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL19426 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL3704258 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL20164915 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL19425 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Cis-Resveratrol SCHEMBL1931746 0.97 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL31096991 0.95 PTGS1 (0.95) PTGS1KDM4ETTRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020198320-A1 METHODS AND COMPOSITIONS RELATED TO ENHANCING RETROVIRAL VECTOR ENTRY AND INTEGRATION IN HOST CELLS THE SCRIPPS RESEARCH INSTITUTE (US) 2020-10-01 WO claimed
WO-2020198320-A1 METHODS AND COMPOSITIONS RELATED TO ENHANCING RETROVIRAL VECTOR ENTRY AND INTEGRATION IN HOST CELLS THE SCRIPPS RESEARCH INSTITUTE (US) 2020-10-01 WO disclosed