Resveratrol

Resveratrol

SCHEMBL20164915

Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1.Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 1.00
KDM4E B2RXH2 5/20 1.00
TTR P02766 5/20 1.00
LMNA P02545 4/20 1.00
MEN1 O00255 4/20 1.00
MAPT P10636 4/20 1.00
KMT2A Q03164 4/20 1.00
CYP1A1 P04798 4/20 1.00
PTGS2 P35354 4/20 1.00
CYP1B1 Q16678 4/20 1.00
ALOX5 P09917 4/20 1.00
ALDH1A1 P00352 3/20 1.00
TP53 P04637 3/20 1.00
CYP1A2 P05177 3/20 1.00
CYP3A4 P08684 3/20 1.00
CYP2C9 P11712 3/20 1.00
HPGD P15428 3/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
HIF1A Q16665 3/20 1.00
HSD17B10 Q99714 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resveratrol SCHEMBL2300985 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Cis-Resveratrol SCHEMBL1931746 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL17629801 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL15106855 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL19425 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL19426 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL3704258 1.00 PTGS1 (1.00) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL31096991 0.97 PTGS1 (0.95) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL3405900 0.97 PTGS1 (0.95) PTGS1KDM4ETTRLMNAMEN1
Resveratrol SCHEMBL22469907 0.97 PTGS1 (0.95) PTGS1KDM4ETTRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210244703-A1 USE OF SCIENTIFICALLY MATCHED PLANT SUPPLEMENTS COMBINED WITH ANTINEOPLASTIC COMPOUNDS FOR THE TREATMENT OF HEMATOLOGICAL MALIGNANCIES Brio Ventures, LLC (US) 2021-08-12 US disclosed
US-10280442-B2 Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols UNIVERSITEIT GENT (BE) 2019-05-07 US disclosed
US-20180142276-A1 MUTANT SUCROSE PHOSPHORYLASES WITH IMPROVED GLYCOSYLATION ACTIVITY TOWARDS POLYPHENOLS UNIVERSITEIT GENT (BE) 2018-05-24 US disclosed
CN-104892478-A Selenized resveratrol preparation for treating cancers SHANGHAI AIQI ECOLOGICAL TECHNOLOGY CO LTD 2015-09-09 CN disclosed
CN-101875600-A Synthesis method for industrially producing resveratrol CHENGDU XINJI TECHNOLOGY CO LTD 2010-11-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10280442-B2 Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols MGAM, GALE, BPGM PTGS1 4221/4885KDM4E 971/4885TTR 1682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.