Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TXN | P10599 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547937 | 0.95 | TBXAS1 (0.45) | TBXAS1TAAR1TERTHTR1AHRH4 | |
| SCHEMBL22471169 | 0.90 | TAAR1 (0.44) | TBXAS1TAAR1TERTHTR1AALOX15 | |
| SCHEMBL20564663 | 0.80 | TAAR1 (0.46) | TAAR1TERTHTR1AALOX15TXN | |
| SCHEMBL1899700 | 0.78 | TBXAS1 (0.49) | TBXAS1TAAR1TERTHTR1AALOX15 | |
| SCHEMBL31366376 | 0.75 | TBXAS1 (0.46) | TBXAS1TAAR1TERTHTR1AALOX15 | |
| SCHEMBL3431746 | 0.74 | TBXAS1 (0.66) | TBXAS1TAAR1TERTHTR1AALOX15 | |
| SCHEMBL9777191 | 0.74 | TBXAS1 (0.60) | TBXAS1TAAR1TERTHTR1AALOX15 | |
| SCHEMBL441515 | 0.74 | TBXAS1 (0.49) | TBXAS1TAAR1TERTHTR1AHRH4 | |
| SCHEMBL7287192 | 0.74 | TBXAS1 (0.49) | TBXAS1TAAR1TERTHTR1AHRH4 | |
| SCHEMBL439546 | 0.73 | TBXAS1 (0.51) | TBXAS1TAAR1TERTHTR1AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020192302-A1 | PYRIMIDINE-CONTAINING TRI-SUBSTITUTED IMIDAZOLE COMPOUND AND APPLICATION THEREOF | 广州必贝特医药技术有限公司 | 2020-10-01 | — | — | WO | disclosed |