⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421305 | 0.93 | TSHR (0.55) | — | |
| SCHEMBL11216994 | 0.92 | TSHR (0.55) | — | |
| SCHEMBL16176008 | 0.91 | ALDH1A1 (0.54) | — | |
| SCHEMBL1930709 | 0.90 | TSHR (0.53) | — | |
| SCHEMBL1940677 | 0.85 | — | — | |
| SCHEMBL8705304 | 0.84 | TSHR (0.47) | — | |
| Methoxymethane SCHEMBL11416469 | 0.83 | HPGD (0.47) | — | |
| Hydrochloric Acid SCHEMBL11161525 | 0.83 | — | — | |
| SCHEMBL11382562 | 0.83 | TSHR (0.65) | — | |
| SCHEMBL18992793 | 0.83 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134516-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | claimed |
| US-8852664-B2 | Neo-menthyl derivatives as flavor materials | SYMRISE AG (DE) | 2014-10-07 | — | — | US | claimed |
| EP-2135516-B1 | Neo-menthyl derivatives as flavourings | SYMRISE AG (DE) | 2012-08-15 | — | — | EP | claimed |
| EP-2135516-A1 | Neo-menthyl derivatives as flavourings | Symrise GmbH & Co. KG (DE) | 2009-12-23 | — | — | EP | claimed |
| US-20090311401-A1 | Neo-Menthyl Derivatives as Flavor Materials | SYMRISE GMBH & CO. KG (DE) | 2009-12-17 | — | — | US | claimed |
| US-7166587-B2 | Carbamic acid alkyl ester derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | HOFFMAN-LA ROCHE INC. | 2005-04-07 | — | — | US | claimed |
| WO-2024134516-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-2789369-B1 | A composition for lightening skin and hair | SYMRISE AG (DE) | 2018-06-06 | — | — | EP | disclosed |
| EP-2842607-B1 | A skin and/or hair whitening mixture | SYMRISE AG (DE) | 2018-05-30 | — | — | EP | disclosed |
| EP-2853254-B1 | A composition for lightening skin and/or hair | SYMRISE AG (DE) | 2017-11-08 | — | — | EP | disclosed |
| EP-2593079-B1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2016-11-16 | — | — | EP | disclosed |
| EP-1866292-A1 | TRICYCLIC 1,2,4-TRIAZINE OXIDES AND COMPOSITIONS THEREFROM FOR THERAPEUTIC USE IN CANCER TREATMENTS | Auckland Uniservices Limited (NZ) | 2007-12-19 | — | — | EP | disclosed |
| WO-2007084786-A1 | PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS | NOVARTIS AG (CH) | 2007-07-26 | — | — | WO | disclosed |
| US-7166587-B2 | Carbamic acid alkyl ester derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-01-23 | — | — | US | disclosed |
| WO-2006104406-A1 | TRICYCLIC 1,2,4-TRIAZINE OXIDES AND COMPOSITIONS THEREFROM FOR THERAPEUTIC USE IN CANCER TREATMENTS | AUCKLAND UNISERVICES LIMITED (NZ) | 2006-10-05 | — | — | WO | disclosed |
| EP-1673347-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. Hoffman-la Roche AG (CH) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040126-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. HOFFMAN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | disclosed |
| US-20050075327-A1 | Carbamic acid alkyl ester derivatives | HOFFMAN-LA ROCHE INC. | 2005-04-07 | — | — | US | disclosed |