Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 12/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395948 | 0.82 | GSK3B (0.55) | DYRK1AGSK3BMAPTRAB9ANPC1 | |
| SCHEMBL13435542 | 0.81 | NPC1 (0.62) | DYRK1AGSK3BMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3490039 | 0.79 | GSK3B (0.66) | DYRK1AGSK3B | |
| SCHEMBL3491930 | 0.78 | GSK3B (0.61) | DYRK1AGSK3BMAPTRAB9ANPC1 | |
| SCHEMBL24653524 | 0.76 | NPC1 (0.65) | GSK3BMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30622710 | 0.76 | NPC1 (0.65) | GSK3BMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3491163 | 0.76 | GSK3B (0.50) | DYRK1AGSK3BMAPTRAB9ANPC1 | |
| SCHEMBL21776965 | 0.74 | NOTUM (0.60) | DYRK1AGSK3BNOTUM | |
| SCHEMBL3491505 | 0.73 | GSK3B (0.83) | GSK3B | |
| SCHEMBL3491221 | 0.72 | GSK3B (0.60) | DYRK1AGSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169640-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3943159-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | Kabushiki Kaisha Yakult Honsha (JP) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020196327-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | 株式会社ヤクルト本社 | 2020-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169640-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | BCKDK, CBR3, NQO2 | DYRK1A 1407/4885GSK3B 2301/4885MAPT 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.