Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | PRNP | P04156 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | DHODH | Q02127 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | UBE2I | P63279 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896811 | 0.82 | DHODH (0.72) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL6309512 | 0.80 | DHODH (0.73) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL13253477 | 0.79 | TP53 (0.56) | RXFP1MEN1KMT2ATP53KDM4E | |
| SCHEMBL1896825 | 0.78 | MEN1 (0.73) | RXFP1MEN1KMT2APRNPPPARG | |
| SCHEMBL1898200 | 0.78 | KMT2A (0.73) | RXFP1MEN1KMT2APRNPPPARG | |
| SCHEMBL6304386 | 0.78 | DHODH (0.74) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL29290339 | 0.78 | DHODH (0.73) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL4461418 | 0.78 | KDM4E (0.74) | RXFP1MEN1KMT2APRNPPPARG | |
| SCHEMBL30064775 | 0.78 | KDM4E (0.74) | RXFP1MEN1KMT2APRNPPPARG | |
| SCHEMBL1899779 | 0.77 | STAT3 (0.73) | MEN1KMT2AKDM4EALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613730-A | Quinoline carboxamide derivative and process for producing intermediate for producing same | 株式会社益力多本社 | 2021-11-05 | — | — | CN | disclosed |
| WO-2020196327-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | 株式会社ヤクルト本社 | 2020-10-01 | — | — | WO | disclosed |