Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309512 | 0.90 | DHODH (0.73) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL1896811 | 0.90 | DHODH (0.72) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL116058 | 0.89 | DHODH (0.71) | DHODHKDM4EPLA2G2AALDH1A1HPGD | |
| SCHEMBL6182924 | 0.89 | DHODH (0.87) | DHODHKDM4EPLA2G2AMAPTALDH1A1 | |
| SCHEMBL6304386 | 0.88 | DHODH (0.74) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL4601899 | 0.88 | DHODH (0.61) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL23590078 | 0.84 | KDM4E (0.65) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL3235591 | 0.84 | PLA2G2A (0.84) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL7823061 | 0.84 | KDM4E (0.79) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 | |
| SCHEMBL245078 | 0.83 | PLA2G2A (0.81) | DHODHKDM4EPLA2G2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613730-A | Quinoline carboxamide derivative and process for producing intermediate for producing same | 株式会社益力多本社 | 2021-11-05 | — | — | CN | disclosed |