Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472884 | 0.90 | CHRM1 (0.46) | EPHX2SMN1; SMN2LMNAGAARAB9A | |
| SCHEMBL22472877 | 0.84 | SMN1; SMN2 (0.38) | EPHX2SMN1; SMN2LMNAGAARAB9A | |
| SCHEMBL22472869 | 0.83 | MAPT (0.45) | EPHX2SMN1; SMN2GAAKDM4ECHRM1 | |
| SCHEMBL22472937 | 0.76 | CHRM1 (0.55) | LMNACHRM1 | |
| SCHEMBL21597937 | 0.75 | CHRM1 (0.48) | EPHX2SMN1; SMN2USP2HPGDCHRM1 | |
| SCHEMBL14978888 | 0.75 | CHRM1 (0.62) | SMN1; SMN2LMNAGAAHPGDCHRM1 | |
| SCHEMBL22472935 | 0.74 | HPGD (0.47) | SMN1; SMN2LMNAHPGDKMT2AALDH1A1 | |
| SCHEMBL27176060 | 0.74 | SMN1; SMN2 (0.39) | EPHX2SMN1; SMN2LMNAGAARAB9A | |
| SCHEMBL22472885 | 0.74 | CHRM1 (0.47) | EPHX2SMN1; SMN2GAAKDM4ECHRM1 | |
| SCHEMBL22472938 | 0.73 | PIK3CD (0.46) | LMNAHCRTR2CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | EPHX2 1688/4885SMN1; SMN2 2514/4885LMNA 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.