Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472944 | 0.90 | CHRM1 (0.67) | CHRM1 | |
| SCHEMBL22472936 | 0.85 | CHRM1 (0.53) | CHRM1DRD2 | |
| SCHEMBL15618571 | 0.79 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL15618702 | 0.78 | CHRM1 (0.70) | CHRM1POLB | |
| SCHEMBL22472869 | 0.76 | MAPT (0.45) | CHRM1POLB | |
| SCHEMBL15630295 | 0.76 | CHRM1 (0.55) | CHRM1DRD2 | |
| SCHEMBL21597926 | 0.76 | CHRM1 (0.63) | CHRM1DRD2 | |
| SCHEMBL22472879 | 0.76 | EPHX2 (0.39) | CHRM1LMNA | |
| SCHEMBL27176055 | 0.75 | CHRM1 (0.49) | CHRM1DRD2LMNAKDM5A | |
| SCHEMBL22472935 | 0.75 | HPGD (0.47) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | CHRM1 1/4885DRD2 200/4885LMNA 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.