Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472932 | 0.90 | OPRM1 (0.45) | BACE1OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL31288712 | 0.87 | BACE1 (0.44) | BACE1OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL22449309 | 0.87 | BACE1 (0.44) | BACE1OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL12084308 | 0.79 | CHRM1 (0.49) | OPRM1OPRL1OPRK1HTR1AHTR2A | |
| SCHEMBL12084263 | 0.79 | OPRL1 (0.48) | BACE1OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL30507197 | 0.79 | OPRM1 (0.53) | BACE1OPRM1OPRL1OPRK1HTR1A | |
| SCHEMBL30507191 | 0.79 | OPRM1 (0.53) | BACE1OPRM1OPRL1OPRK1HTR1A | |
| SCHEMBL12084376 | 0.78 | OPRL1 (0.44) | BACE1OPRM1OPRL1OPRK1HTR1A | |
| SCHEMBL12084836 | 0.78 | OPRL1 (0.46) | BACE1OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL12084317 | 0.77 | OPRL1 (0.47) | BACE1OPRM1OPRL1OPRK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | BACE1 1018/4885OPRM1 39/4885OPRL1 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.