Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473808 | 1.00 | EPHX2 (0.45) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL19249122 | 0.99 | EPHX2 (0.43) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL21106554 | 0.89 | EPHX2 (0.45) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL22473663 | 0.89 | KMT2A (0.41) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL22473697 | 0.89 | KMT2A (0.41) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL22473711 | 0.89 | KMT2A (0.41) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL26700977 | 0.87 | EPHX2 (0.43) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL25591284 | 0.87 | EPHX2 (0.43) | EPHX2LMNAGLP1RALDH1A1KMT2A | |
| SCHEMBL22473696 | 0.87 | TSHR (0.42) | EPHX2GLP1RALDH1A1KMT2AFAAH | |
| SCHEMBL22473620 | 0.87 | GLP1R (0.43) | EPHX2LMNAGLP1RALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787443-B2 | RAF-degrading conjugate compounds | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787443-B2 | RAF-degrading conjugate compounds | BRAF, RAF1, ARAF | EPHX2 557/4885LMNA 3373/4885GLP1R 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.