Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473808 | 0.87 | EPHX2 (0.45) | GLP1REPHX2FAAHLMNAALDH1A1 | |
| SCHEMBL22473699 | 0.87 | EPHX2 (0.45) | GLP1REPHX2FAAHLMNAALDH1A1 | |
| SCHEMBL19249122 | 0.85 | EPHX2 (0.43) | GLP1REPHX2FAAHLMNAALDH1A1 | |
| SCHEMBL25832913 | 0.85 | TSHR (0.43) | GLP1REPHX2FAAHALDH1A1TSHR | |
| SCHEMBL25110641 | 0.84 | TSHR (0.48) | GLP1REPHX2FAAHALDH1A1TSHR | |
| SCHEMBL25729686 | 0.83 | EPHX2 (0.43) | GLP1REPHX2FAAHALDH1A1TSHR | |
| SCHEMBL24673744 | 0.82 | EPHX2 (0.44) | GLP1REPHX2FAAHTSHRRECQL | |
| SCHEMBL25123586 | 0.82 | TSHR (0.40) | GLP1REPHX2FAAHALDH1A1TSHR | |
| SCHEMBL22473660 | 0.79 | EPHX2 (0.46) | GLP1REPHX2FAAHLMNAALDH1A1 | |
| SCHEMBL22906477 | 0.77 | FAAH (0.53) | EPHX2FAAHTSHRRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787443-B2 | RAF-degrading conjugate compounds | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787443-B2 | RAF-degrading conjugate compounds | BRAF, RAF1, ARAF | GLP1R 3880/4885EPHX2 557/4885FAAH 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.