Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15471480 | 1.00 | FFAR1 (0.56) | FFAR1FFAR4CYP2C8CYP2C9EDNRB | |
| SCHEMBL16855673 | 0.94 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL16829648 | 0.94 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL16846007 | 0.94 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL29423892 | 0.94 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL15471342 | 0.93 | FFAR1 (0.48) | FFAR1WDR5CYP11B1CYP11B2 | |
| SCHEMBL15471425 | 0.92 | FFAR1 (0.57) | FFAR1FFAR4CYP2C8CYP2C9EDNRB | |
| SCHEMBL15471423 | 0.92 | FFAR1 (0.57) | FFAR1FFAR4CYP2C8CYP2C9EDNRB | |
| SCHEMBL16884587 | 0.92 | FFAR1 (0.57) | FFAR1FFAR4CYP2C8CYP2C9EDNRB | |
| SCHEMBL15464467 | 0.90 | FFAR1 (0.62) | FFAR1FFAR4CYP2C8CYP2C9DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880028-B1 | ANTIDIABETIC TRICYCLIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-09-30 | — | — | EP | disclosed |