Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16846007 | 1.00 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL16829648 | 1.00 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL16855673 | 1.00 | FFAR1 (0.51) | FFAR1CD274FFAR4EGFRALKBH1 | |
| SCHEMBL15471480 | 0.94 | FFAR1 (0.56) | FFAR1FFAR4 | |
| SCHEMBL22474739 | 0.94 | FFAR1 (0.56) | FFAR1FFAR4 | |
| SCHEMBL29423955 | 0.92 | FFAR1 (0.45) | FFAR1CD274FFAR4 | |
| SCHEMBL23952772 | 0.91 | FFAR1 (0.56) | FFAR1CD274FFAR4 | |
| SCHEMBL18963536 | 0.91 | FFAR1 (0.56) | FFAR1CD274FFAR4 | |
| SCHEMBL16845976 | 0.91 | FFAR1 (0.56) | FFAR1CD274FFAR4 | |
| SCHEMBL19670781 | 0.91 | FFAR1 (0.56) | FFAR1CD274FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |