SCHEMBL2247499

SCHEMBL2247499

C=C[Si](CC)(OCCCC)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ATM Q13315 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27396571 0.94 TSHR (0.34) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL22654306 0.93 TSHR (0.34) TSHRHPGDALDH1A1
SCHEMBL930777 0.86 TSHR (0.38) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL931015 0.86 TSHR (0.38) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL2247641 0.86
SCHEMBL931827 0.84 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL5834121 0.84 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL931795 0.84 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL2240233 0.84 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL22661026 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101484131-B Cosmetic hair preparation SHISEIDO CO LTD 2014-06-25 CN disclosed
US-7994250-B2 Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof KONISHI CO., LTD. (JP) 2011-08-09 US disclosed
EP-1398353-B1 THERMOPLASTIC RESIN COMPOSITION KANEKA CORP (JP) 2010-10-13 EP disclosed
US-20090326151-A1 HAIR COSMETIC KONISHI CO., LTD. (JP) 2009-12-31 US disclosed
CN-101484131-A Cosmetic hair preparation SHISEIDO CO LTD (JP) 2009-07-15 CN disclosed
CN-100484986-C Vinyl-urethane copolymer and method for producing same KONISHI CO LTD (JP) 2009-05-06 CN disclosed
EP-2039347-A1 COSMETIC HAIR PREPARATION Shiseido Company, Limited (JP) 2009-03-25 EP disclosed
US-7282535-B2 Thermoplastic resin composition KANEKA CORPORATION (JP) 2007-10-16 US disclosed
EP-1837360-A1 VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME Konishi Co., Ltd. (JP) 2007-09-26 EP disclosed
CN-101016400-A Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 2007-08-15 CN disclosed
US-20070117902-A1 Vinyl-urethane copolymers and production methods thereof KONISHI CO., LTD. (JP) 2007-05-24 US disclosed
CN-1315949-C Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 2007-05-16 CN disclosed
CN-1914252-A Vinyl-urethane copolymer and process for producing the same KONISHI CO LTD (JP) 2007-02-14 CN disclosed
US-7005532-B2 Process of producing alkoxysilanes TOAGOSEI CO., LTD. (JP) 2006-02-28 US disclosed
US-20050020845-A1 Process of producing alkoxysilanes TOAGOSEI CO., LTD. (JP) 2005-01-27 US disclosed
US-20040147674-A1 Thermoplastic resin composition KANEKA CORPORATION (JP) 2004-07-29 US disclosed
CN-1509318-A Thermoplastic resin composition ��Ԩ��ѧ��ҵ��ʽ���� 2004-06-30 CN disclosed
EP-1428828-A1 PROCESS FOR PREPARATION OF ALKOXYSILANES TOAGOSEI CO., LTD. (JP) 2004-06-16 EP disclosed
EP-1398353-A1 THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2004-03-17 EP disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed