SCHEMBL22476609

SCHEMBL22476609

Cc1cc(C)c(C2=NCCN2)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 16/20 0.55
HTR1D P28221 1/20 0.53
HTR1B P28222 1/20 0.53
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11297597 0.87 NISCH (0.47) NISCHHTR1DHTR1BKDM4ELMNA
SCHEMBL11516541 0.77 NISCH (0.66) NISCHLMNA
SCHEMBL23902200 0.71 NISCH (0.68) NISCHHTR1DLMNA
SCHEMBL3742115 0.71 NISCH (0.56) NISCHLMNA
SCHEMBL1886692 0.71 NISCH (1.00) NISCHHTR1DLMNA
SCHEMBL6992574 0.70 NISCH (0.72) NISCHHTR1DKDM4ELMNA
Hydrochloric Acid SCHEMBL23880726 0.70 NISCH (0.66) NISCHHTR1DLMNA
SCHEMBL953076 0.69 HTR1D (1.00) NISCHHTR1DHTR1BLMNA
SCHEMBL14286968 0.69 NISCH (0.56) NISCHKDM4ELMNA
SCHEMBL30382864 0.69 NISCH (0.56) NISCHKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117659065-A Method for preparing beta-boron-substituted aldehyde derivative 中国科学院大连化学物理研究所 2024-03-08 CN claimed
CN-117659065-A Method for preparing beta-boron-substituted aldehyde derivative 中国科学院大连化学物理研究所 2024-03-08 CN disclosed
EP-3250208-B1 7-BENZYL-4-(4-(TRIFLUOROMETHYL)BENZYL)-1,2,6,7,8,9-HEXAHYDROIMIDAZO[1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5(4H)-ONE AND SALTS THEREOF AND THEIR USE IN THERAPY ONCOCEUTICS INC (US) 2020-09-30 EP disclosed