Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 15/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22476609 | 0.87 | NISCH (0.55) | NISCHHTR1DHTR1BLMNAKDM4E | |
| SCHEMBL5828216 | 0.72 | NISCH (0.49) | NISCHHTR1DLMNA | |
| SCHEMBL30982282 | 0.72 | NISCH (0.58) | NISCHHTR1DKDM4E | |
| SCHEMBL11516541 | 0.70 | NISCH (0.66) | NISCHLMNA | |
| SCHEMBL5827257 | 0.68 | NISCH (0.53) | NISCH | |
| SCHEMBL4389092 | 0.66 | NISCH (0.49) | NISCHHTR1DHTR1B | |
| SCHEMBL23902200 | 0.65 | NISCH (0.68) | NISCHHTR1DLMNA | |
| SCHEMBL3742115 | 0.65 | NISCH (0.56) | NISCHLMNA | |
| SCHEMBL16275243 | 0.64 | NISCH (0.60) | NISCHLMNAKDM4E | |
| SCHEMBL1886692 | 0.64 | NISCH (1.00) | NISCHHTR1DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046446-A1 | Polyazaheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |