Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319903 | 0.94 | TSHR (0.44) | GRM2ESR1ESR2TSHRKCNH2 | |
| SCHEMBL25457245 | 0.83 | ESR1 (0.52) | KIF11RXRARXRBRXRGESR1 | |
| SCHEMBL25587208 | 0.80 | TSHR (0.44) | ESR1ESR2TSHRKCNH2TP53 | |
| SCHEMBL28621845 | 0.78 | IDO1 (0.41) | ACHEKDM4ENPC1RAB9A | |
| SCHEMBL18471306 | 0.77 | TSHR (0.41) | ESR1ESR2TSHRKCNH2TP53 | |
| SCHEMBL34472339 | 0.77 | SLC6A2 (0.47) | KIF11MAOBESR1ESR2KDM4E | |
| SCHEMBL24871287 | 0.77 | KCNH2 (0.44) | ESR1ESR2TSHRKCNH2TP53 | |
| SCHEMBL3423876 | 0.76 | KIF11 (0.70) | KIF11TSHRTP53BCHEACHE | |
| SCHEMBL7670360 | 0.76 | ESR1 (0.38) | MAOBESR1ESR2TSHR | |
| SCHEMBL26915 | 0.76 | KIF11 (0.70) | KIF11TSHRTP53BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308341-A1 | POLYMERS HAVING STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES | UNIVERSITY OF DELAWARE | 2020-10-01 | — | — | US | disclosed |