Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | PMM2 | O15305 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339892 | 0.80 | IDO1 (0.45) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL24444921 | 0.80 | IDO1 (0.36) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL1609993 | 0.74 | CYP2A6 (0.42) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL18550534 | 0.72 | IDO1 (0.36) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL27416204 | 0.72 | IDO1 (0.42) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL6404079 | 0.72 | MCL1 (0.54) | IDO1MAPTRAB9ABCL2L1MCL1 | |
| SCHEMBL12778296 | 0.71 | GPR3 (0.50) | IDO1MAPTRAB9AMCL1 | |
| SCHEMBL825667 | 0.70 | CYP2A6 (0.39) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL16785723 | 0.70 | PIM1 (0.42) | IDO1CYP2A6PARP15PARP10TNKS2 | |
| SCHEMBL17969060 | 0.69 | CYP17A1 (0.40) | KIF11PMM2G6PDMPIPHOSPHO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198435-A1 | SMALL MOLECULE DEGRADERS OF STAT3 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-10-01 | — | — | WO | disclosed |