Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31559320 | 0.86 | OPRK1 (0.45) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL22479315 | 0.85 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL31330332 | 0.83 | OPRK1 (0.46) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL31559318 | 0.83 | OPRK1 (0.46) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL22471461 | 0.83 | OPRL1 (0.47) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL22479463 | 0.82 | OPRK1 (0.44) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL8320599 | 0.81 | OPRL1 (0.67) | OPRL1OPRM1OPRK1OPRD1EGLN1 | |
| SCHEMBL22471605 | 0.80 | OPRK1 (0.41) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL21904556 | 0.80 | OPRK1 (0.41) | OPRL1OPRM1OPRK1OPRD1MAPT | |
| SCHEMBL30898612 | 0.80 | OPRK1 (0.41) | OPRL1OPRM1OPRK1OPRD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950682-B1 | PREPARATION METHOD FOR AMIDE COMPOUNDS AND USE THEREOF IN MEDICAL FIELD | SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO LTD (CN) | 2026-02-11 | — | — | EP | disclosed |
| US-12473298-B2 | Amide compounds, preparation method therefor, and use thereof in the medical field | SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-3950682-A1 | PREPARATION METHOD FOR AMIDE COMPOUNDS AND USE THEREOF IN MEDICAL FIELD | Shanghai Synergy Pharmaceutical Sciences Co., Ltd (CN) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020192652-A1 | PREPARATION METHOD FOR AMIDE COMPOUNDS AND USE THEREOF IN MEDICAL FIELD | 上海华汇拓医药科技有限公司 | 2020-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473298-B2 | Amide compounds, preparation method therefor, and use thereof in the medical field | EZH2, IKZF2, EZH1 | OPRL1 4833/4885OPRM1 4637/4885OPRK1 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.