SCHEMBL224794

SCHEMBL224794

O=[N+]([O-])c1ccc(Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 3/20 1.00
L3MBTL1 Q9Y468 3/20 1.00
HPGD P15428 1/20 1.00
CXCR2 P25025 1/20 0.76
ALDH1A1 P00352 7/20 0.62
LMNA P02545 3/20 0.62
MEN1 O00255 7/20 0.62
KMT2A Q03164 7/20 0.62
MAPT P10636 6/20 0.62
MAPK1 P28482 5/20 0.62
TDP1 Q9NUW8 4/20 0.62
HTT P42858 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
KDM4E B2RXH2 2/20 0.62
GLA P06280 1/20 0.62
KIF11 P52732 1/20 0.60
CA12 O43570 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
PTPRF P10586 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479463 1.00 ALOX12 (1.00) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL9717470 0.98 ALOX12 (0.96) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
Hydrochloric Acid SCHEMBL3693418 0.98 ALOX12 (0.96) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL14819032 0.94 ALOX12 (0.89) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL4957626 0.91 HPGD (0.83) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL18289622 0.91 HPGD (0.83) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL18289621 0.91 HPGD (0.83) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL395942 0.91 HPGD (0.83) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL11341841 0.90 HPGD (0.81) ALOX12L3MBTL1HPGDCXCR2ALDH1A1
SCHEMBL769328 0.89 HPGD (0.79) ALOX12L3MBTL1HPGDCXCR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1003 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899113-A Method for preparing RT pessary condensation liquid by falling film reaction 中国石油化工股份有限公司 2025-04-29 CN claimed
CN-119899112-A Process for preparing RT pessary condensation liquid by falling film reaction 中国石油化工股份有限公司 2025-04-29 CN claimed
CN-119800426-A Electrode for synthesizing RT pessary, preparation method and application 万华化学集团股份有限公司 2025-04-11 CN claimed
CN-118924921-A Preparation method of near infrared two-region cyanine dye for improving fluorescence brightness 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-11-12 CN claimed
CN-118834133-A Production process of diphenylamine 南通新邦化工科技有限公司 2024-10-25 CN claimed
CN-118217660-A Device and method for purifying phenazine mixture as byproduct in production of RT (reverse transcription) pessary by nitrobenzene method 山东尚舜化工有限公司 2024-06-21 CN claimed
CN-118004997-A Preparation method of pore-diameter-adjustable porous carbon material 东南大学 2024-05-10 CN claimed
CN-117774468-A Multilayer sandwich structure pressure color-changing film and preparation method and application thereof 中山大学 2024-03-29 CN claimed
CN-117414878-A Impurity removal and recovery method for waste catalyst in aniline-nitrobenzene condensation reaction 青岛科技大学 2024-01-19 CN claimed
CN-117402071-A Post-treatment method of aniline-nitrobenzene condensation reducing solution 青岛科技大学 2024-01-16 CN claimed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US claimed
EP-0084527-A2 Process for producing paraphenylenediamine mixtures MONSANTO COMPANY (US) 1983-07-27 EP claimed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP claimed
US-4304939-A Preparation of N-phenyl-N-alkylphenylenediamines UOP INC. (US) 1981-12-08 US claimed
US-4216039-A Smokeless propellant compositions having polyester or polybutadiene binder system crosslinked with nitrocellulose THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1980-08-05 US claimed
US-4209463-A Promoting the formation of nitrodiarylamines from nitrohaloarenes, activated aryl amines and sodium carbonates MONSANTO COMPANY (US) 1980-06-24 US claimed
US-4187248-A FORMANILIDE MONSANTO COMPANY (US) 1980-02-05 US claimed
US-4187249-A COMPOUNDS OF POTASSIUM, CESIUM, OR RUBIDIUM MONSANTO COMPANY (US) 1980-02-05 US claimed
US-4155936-A Para-nitrodiphenylamines synthesis using Polyethers and macrocyclic esters as solubilizing agents THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-05-22 US claimed
US-4140716-A Process for making an amide of formic acid and forming nitrodiarylamine therefrom MONSANTO COMPANY (US) 1979-02-20 US claimed