SCHEMBL224801

SCHEMBL224801

Nc1ccc2cccc(SSc3cccc4ccc(N)cc34)c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.57
ALDH1A1 P00352 8/20 0.46
HSD17B10 Q99714 6/20 0.46
CYP3A4 P08684 4/20 0.46
CASP1 P29466 4/20 0.45
ALOX15 P16050 2/20 0.45
CASP7 P55210 2/20 0.45
HBB P68871 1/20 0.45
HIF1A Q16665 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ITGB2 P05107 1/20 0.44
ICAM1 P05362 1/20 0.44
ITGAL P20701 1/20 0.44
PLAU P00749 2/20 0.42
RECQL P46063 1/20 0.39
HTR3A P46098 1/20 0.38
MEN1 O00255 6/20 0.38
KMT2A Q03164 6/20 0.38
MAPT P10636 6/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224693 0.83 PLAU (0.57) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL12377533 0.76 CTDSP1 (0.63) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL29405526 0.76 CTDSP1 (0.63) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL729842 0.76 CTDSP1 (0.63) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL29498396 0.76 CTDSP1 (0.63) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL8463060 0.75 MCL1 (0.52) ALDH1A1HSD17B10CYP3A4ALOX15HIF1A
SCHEMBL12774936 0.74 CTDSP1 (0.58) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL29402125 0.74 CTDSP1 (0.58) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL1758257 0.73 ALDH1A1 (0.64) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL23043133 0.72 CTDSP1 (0.59) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 561 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 US disclosed
US-20200197757-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-06-25 US disclosed
US-10596419-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2020-03-24 US disclosed
US-20200086174-A1 A GOLF BALL COMPRISING A VERY-LOW MELT FLOW INNER COVER LAYER COMPOSITION JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2020-03-19 US disclosed
US-20200047033-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-02-13 US disclosed
US-10478674-B2 Golf ball comprising a very-low melt flow inner cover layer composition ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-10478675-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5816939-A AGING RESISTANCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1998-10-06 US disclosed