SCHEMBL22480304

SCHEMBL22480304

C=C(C)C(=O)OCC(CC)(COC(=O)C(C)CN1CCOCC1)COC(=O)C(C)CN1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
LMNA P02545 4/20 0.41
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
GAA P10253 1/20 0.36
NPC1 O15118 1/20 0.36
KDM4E B2RXH2 1/20 0.34
TSHR P16473 2/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 2/20 0.34
ABCB1 P08183 1/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
JAK2 O60674 2/20 0.34
PAX8 Q06710 1/20 0.34
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
THRB P10828 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MITF O75030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22480296 1.00 ALDH1A1 (0.45) ALDH1A1LMNACYP3A4CYP2C19GAA
SCHEMBL22480293 0.90 ALDH1A1 (0.54) ALDH1A1LMNACYP3A4CYP2C19GAA
SCHEMBL29419952 0.80 ALDH1A1 (0.38) ALDH1A1LMNACYP3A4CYP2C19GAA
Oxirane SCHEMBL5127267 0.79 ALDH1A1 (0.43) ALDH1A1GAATSHRTHRB
SCHEMBL14999267 0.79 TSHR (0.53) ALDH1A1LMNACYP3A4CYP2C19TSHR
SCHEMBL12661079 0.78 TSHR (0.44) ALDH1A1TSHRTHRB
Isobutane SCHEMBL21625539 0.76 TSHR (0.52) ALDH1A1TSHRHTTTHRB
SCHEMBL13892527 0.74 TSHR (0.47) ALDH1A1TSHRMAPTTHRB
SCHEMBL11668730 0.74 ALDH1A1 (0.62) ALDH1A1LMNACYP3A4CYP2C19GAA
SCHEMBL2578370 0.74 TSHR (0.45) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200308425-A1 ACTIVE-ENERGY-RAY-CURABLE COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, COMPOSITION STORED CONTAINER, TWO-DIMENSIONAL OR THREE-DIMENSIONAL IMAGE FORMING APPARATUS, TWO-DIMENSIONAL OR THREE-DIMENSIONAL IMAGE FORMING METHOD, CURED MATERIAL, AND DECORATED ARTICLE TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2020-10-01 US disclosed