Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 14/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 14/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 14/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 14/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 7/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 7/20 | 0.48 |
| ▸ | GRIK4 | Q16099 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181851 | 0.82 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8095672 | 0.80 | GRIA1 (0.51) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8091804 | 0.78 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8340446 | 0.77 | GRIA1 (0.50) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8346010 | 0.74 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8083730 | 0.74 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7360391 | 0.73 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8098793 | 0.73 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8122798 | 0.73 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8107335 | 0.73 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308539-A1 | AFFINITY-TAGGED PHOTOSWITCHES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308539-A1 | AFFINITY-TAGGED PHOTOSWITCHES AND METHODS OF USE THEREOF | CD2BP2, AGBL2, CLTB | GRIA1 1906/4885GRIA2 1689/4885GRIA3 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.